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Comparison To Other Treatments

Other treatment options for prostate cancer have come and gone over the past 20  years, such as Cryotherapy, HIFU, and Cyberknife. None of these modalities have proven themselves after sufficient follow-up, over 10 years, to have long standing efficacy and/or low toxicity.

Prostatectomy and external beam radiation alone have a long history of proven efficacy in the treatment of prostate cancer and are a valid alternative to brachytherapy.  Both of these modalities have their own risks and toxicity profiles.

Recently, the Cleveland Clinic announced the results of a comprehensive retrospective study of Medicare aged patients comparing brachytherapy (seed implant) with prostatectomy and external beam radiation in the treatment of localized prostate cancer. Their results, with over 137,000 patients and up to 16 years of follow-up, showed seed implant to be the most cost effective and least toxic treatment. Cure rates with seeds were equivalent to surgery.

Ultimately, it is the patient’s decision as to which proven modality best fits into their outcome goals and lifestyle.