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RECURRENCE.Those patients who underwent primary treatment with conventional EBRT or seed implant alone who are eligible for salvage of an initial failure after extensive workup ruling out gross extracapsular extension or distant metastasis.
Staging workup may include: pathologic biopsy confirming location, volume of cancer prostate ultrasound using spectral color flow doppler PSA (using the most sophisticated assays available) prostatic acid phosphatase (PAP) CT (helical) or MRI (endo-rectal coil) bone scan prostascint RT-PCR (when available), BioStage digital rectal exam (DRE) pathologic slide review (note) many of the above staging studies may also be utilized for low-risk, intermediate and high-risk evaluation |